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Volume 15, Issue 1 (Iranian Journal of Breast Diseases 2022)
ijbd 2022, 15(1): 46-58 |
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Abd Ali Shihad A, Adnan Yousif Alkamolei B, Abdulkadhum Nasser H. The Clinical and Prognostic Significance of Triple-Negative Status Invasive Breast Cancer in a Sample of Iraqi Women. ijbd 2022; 15 (1) :46-58
URL: http://ijbd.ir/article-1-965-en.html
URL: http://ijbd.ir/article-1-965-en.html
1- M.B.Ch.B, FICMS, Diwaniya Teaching, Hospital, Iraq , ahmedabdali015@gmail.com
2- M.B.Ch.B, FICMS, Diwaniya Teaching, Hospital, Iraq
3- M.B.Ch.B, FICMS, Imam Al_Hussain Medical City, Iraq
2- M.B.Ch.B, FICMS, Diwaniya Teaching, Hospital, Iraq
3- M.B.Ch.B, FICMS, Imam Al_Hussain Medical City, Iraq
Abstract: (1756 Views)
Introduction: Triple-negative breast cancer (TNBC) is a type of breast cancer that is negative for estrogen receptor, progesterone receptor, and HER2. This study aimed to evaluate the clinical outcomes and short-term prognosis of this type of cancer compared with other subtypes of breast cancer.
Methods: A cross-sectional study was conducted on 108 women with invasive breast cancer. The patients were divided into a TNBC or a non-TNBC group. Multiple clinicopathological variables, diagnostic modality reports, progression-free survival, and overall survival were assessed.
Results: The results showed no statistically significant difference between the TNBC group and the non-TNBC group in age, BMI, or family history of breast cancer. In the TNBC group, compared with the non-TNBC group, the presence grade 3 tumor and lymphovascular invasion were significantly higher (P = 0.02 and P = 0.014, respectively). Progression-free survival rates in the TNBC and non-TNBC groups were 81.4% and 90.9%, and overall survival in the two groups were 93.8% and 93%, respectively.
Conclusion: There was a significant difference between the two groups in the form of histologic grade and presence of lymphovascular invasion. Non-significant differences in progression-free survival and overall survival between the two groups may be due to the short duration of follow-up.
Methods: A cross-sectional study was conducted on 108 women with invasive breast cancer. The patients were divided into a TNBC or a non-TNBC group. Multiple clinicopathological variables, diagnostic modality reports, progression-free survival, and overall survival were assessed.
Results: The results showed no statistically significant difference between the TNBC group and the non-TNBC group in age, BMI, or family history of breast cancer. In the TNBC group, compared with the non-TNBC group, the presence grade 3 tumor and lymphovascular invasion were significantly higher (P = 0.02 and P = 0.014, respectively). Progression-free survival rates in the TNBC and non-TNBC groups were 81.4% and 90.9%, and overall survival in the two groups were 93.8% and 93%, respectively.
Conclusion: There was a significant difference between the two groups in the form of histologic grade and presence of lymphovascular invasion. Non-significant differences in progression-free survival and overall survival between the two groups may be due to the short duration of follow-up.
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Conclusion: There was a significant difference between the two groups in the form of histologic grade and presence of lymphovascular invasion. Non-significant differences in progression-free survival and overall survival between the two groups may be due to the short duration of follow-up.
Type of Study: Research |
Received: 2022/02/1 | Accepted: 2022/03/9 | Published: 2022/04/30
Received: 2022/02/1 | Accepted: 2022/03/9 | Published: 2022/04/30
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