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Volume 18, Issue 1 (Iranian Journal of Breast Diseases 2025)
ijbd 2025, 18(1): 94-106 |
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Akrami M, Geramifar P, Tavakolian N, Ghoddusi Johari M, Kalantari meibodi M. Investigating the Accuracy of Magnetic Resonance Imaging in the Diagnosis of Multifocal and Multicentric Breast Cancer: A Cross-Sectional Study. ijbd 2025; 18 (1) :94-106
URL: http://ijbd.ir/article-1-1126-en.html
URL: http://ijbd.ir/article-1-1126-en.html
Majid Akrami1 
, Pardis Geramifar2 , Nastaran Tavakolian3 , Masoumeh Ghoddusi Johari *4 , Mohammad Kalantari meibodi2
, Pardis Geramifar2 , Nastaran Tavakolian3 , Masoumeh Ghoddusi Johari *4 , Mohammad Kalantari meibodi2
1- Shiraz university of medical sciences
2- Medical Faculty, Kazerun Branch, Islamic Azad University, Kazerun, Iran
3- Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4- Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran ,m.ghoddusi94@yahoo.com
2- Medical Faculty, Kazerun Branch, Islamic Azad University, Kazerun, Iran
3- Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4- Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran ,
Abstract: (251 Views)
Introduction: With the rising incidence of breast cancer, the need for an effective diagnostic method, particularly in multifocal and multicenter breast cancers, becomes increasingly urgent. The present study aimed to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting multifocal and multicentric breast cancers.
Materials and Methods: This study was conducted cross-sectionally. The study population included patients with breast cancer who underwent MRI before surgery. The sample required for the study was collected through the census method. The Mc Nemar test was used to compare the results of the two methods of pathology and MRI. In addition, the Receiver Operating Characteristic (ROC) curve was used to determine the accuracy of MRI in diagnosing multifocal and multicentric breast cancers. All analyses were conducted using SPSS software (version 22).
Results: In general, 94 patients were included in the study. The average age of the patients was 45.03 ± 11.37 years. Of the 21 cases reported based on the MRI results of the multifocal cancer, 9 (42.9%) had pathology consistent with the MRI results (P=0.238). The sensitivity, specificity, accuracy, and area under the curve (AUC) for the MRI diagnostic method were calculated as 60%, 86.1%, 80.8%, and 73% (CI 95%: 57.4 – 88.6), respectively.
Conclusion: Based on the research findings, this high specificity level contributes to the overall accuracy of MRI as a diagnostic tool, supporting its use in the diagnosis of multifocal and multicentric breast cancers.
Materials and Methods: This study was conducted cross-sectionally. The study population included patients with breast cancer who underwent MRI before surgery. The sample required for the study was collected through the census method. The Mc Nemar test was used to compare the results of the two methods of pathology and MRI. In addition, the Receiver Operating Characteristic (ROC) curve was used to determine the accuracy of MRI in diagnosing multifocal and multicentric breast cancers. All analyses were conducted using SPSS software (version 22).
Results: In general, 94 patients were included in the study. The average age of the patients was 45.03 ± 11.37 years. Of the 21 cases reported based on the MRI results of the multifocal cancer, 9 (42.9%) had pathology consistent with the MRI results (P=0.238). The sensitivity, specificity, accuracy, and area under the curve (AUC) for the MRI diagnostic method were calculated as 60%, 86.1%, 80.8%, and 73% (CI 95%: 57.4 – 88.6), respectively.
Conclusion: Based on the research findings, this high specificity level contributes to the overall accuracy of MRI as a diagnostic tool, supporting its use in the diagnosis of multifocal and multicentric breast cancers.
Keywords: Breast Cancer, Magnetic Resonance Imaging, Multicentric Cancer, Multifocal Cancer, ROC Curve
Type of Study: Research |
Subject:
Diagnosis, treatment, rehabilitation
Received: 2024/07/21 | Accepted: 2024/11/18 | Published: 2025/03/19
Received: 2024/07/21 | Accepted: 2024/11/18 | Published: 2025/03/19
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