Majid Akrami, Pardis Geramifar, Miss Nastaran Tavakolian, Masoumeh Ghoddusi Johari, Mohammad Kalantari Meibodi,
Volume 18, Issue 1 (Iranian Journal of Breast Diseases 2025)
Introduction: With the rising incidence of breast cancer, the need for an effective diagnostic method, particularly in multifocal and multicenter breast cancers, becomes increasingly urgent. The present study aimed to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting multifocal and multicentric breast cancers.
Materials and Methods: This study was conducted cross-sectionally. The study population included patients with breast cancer who underwent MRI before surgery. The sample required for the study was collected through the census method. The Mc Nemar test was used to compare the results of the two methods of pathology and MRI. In addition, the Receiver Operating Characteristic (ROC) curve was used to determine the accuracy of MRI in diagnosing multifocal and multicentric breast cancers. All analyses were conducted using SPSS software (version 22).
Results: In general, 94 patients were included in the study. The average age of the patients was 45.03 ± 11.37 years. Of the 21 cases reported based on the MRI results of the multifocal cancer, 9 (42.9%) had pathology consistent with the MRI results (P=0.238). The sensitivity, specificity, accuracy, and area under the curve (AUC) for the MRI diagnostic method were calculated as 60%, 86.1%, 80.8%, and 73% (CI 95%: 57.4 – 88.6), respectively.
Conclusion: Based on the research findings, this high specificity level contributes to the overall accuracy of MRI as a diagnostic tool, supporting its use in the diagnosis of multifocal and multicentric breast cancers.
