The impact of COVID-19 on breast cancer recurrence: A brief review

Fatemeh, Elmi; Aghajanizadeh, Maryam; Ghanbari Motlagh, Ali; Mafi, Ahmad

doi:10.30699/ijbd.15.4.129

Volume 15, Issue 4 (Iranian Journal of Breast Diseases 2022) ijbd 2022, 15(4): 129-140 | Back to browse issues page

‎ 10.30699/ijbd.15.4.129

‎ 20.1001.1.17359406.1401.15.4.8.8

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Fatemeh E, Aghajanizadeh M, Ghanbari Motlagh A, Mafi A. The impact of COVID-19 on breast cancer recurrence: A brief review. ijbd 2022; 15 (4) :129-140
URL: http://ijbd.ir/article-1-1008-en.html

The impact of COVID-19 on breast cancer recurrence: A brief review

Elmi Fatemeh¹

, Maryam Aghajanizadeh¹

, Ali Ghanbari Motlagh¹

, Ahmad Mafi

1- Radiation Oncology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, Iran
2- Radiation Oncology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, Iran , ahmadrmafi@yahoo.com

Abstract: (411 Views)

COVID-19 has affected several aspects of healthcare systems worldwide. While our understanding of the impact of cancer and its treatment on COVID-19 mortality is improving, there is still little known regarding the possible mechanisms by which COVID-19 might interfere with cancer cells, especially breast cancer. Several factors activated during COVID-19 have been implicated in tumorigenesis and the development of metastasis. Inflammation, hypoxia, reduced levels of angiotensin converting enzyme 2, elevated levels of Interleukin 6 and some other cytokines that are hallmarks of COVID-19 are capable of inducing tumor relapse and metastasis. Understanding the interaction between COVID-19 and breast cancer tumor cells is essential for evaluating the potential long-term risks of COVID-19 in the patients, and for scheduling necessary preventive, screening and therapeutic interventions.