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Volume 15, Issue 4 (Iranian Journal of Breast Diseases 2023)
ijbd 2023, 15(4): 129-140 |
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Fatemeh E, Aghajanizadeh M, Ghanbari Motlagh A, Mafi A. The impact of COVID-19 on breast cancer recurrence: A brief review. ijbd 2023; 15 (4) :129-140
URL: http://ijbd.ir/article-1-1008-en.html
URL: http://ijbd.ir/article-1-1008-en.html
1- Radiation Oncology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, Iran
2- Radiation Oncology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, Iran ,ahmadrmafi@yahoo.com
2- Radiation Oncology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, Iran ,
Abstract: (1609 Views)
COVID-19 has affected several aspects of healthcare systems worldwide. While our understanding of the impact of cancer and its treatment on COVID-19 mortality is improving, there is still little known regarding the possible mechanisms by which COVID-19 might interfere with cancer cells, especially breast cancer. Several factors activated during COVID-19 have been implicated in tumorigenesis and the development of metastasis. Inflammation, hypoxia, reduced levels of angiotensin converting enzyme 2, elevated levels of Interleukin 6 and some other cytokines that are hallmarks of COVID-19 are capable of inducing tumor relapse and metastasis. Understanding the interaction between COVID-19 and breast cancer tumor cells is essential for evaluating the potential long-term risks of COVID-19 in the patients, and for scheduling necessary preventive, screening and therapeutic interventions.
Keywords: COVID-19, cancer, breast, relapse, metastasis, inflammation, dormant cancer cells, neutrophil extracellular traps, interleukins, angiotensin converting enzyme
Type of Study: review |
Subject:
Diagnosis, treatment, rehabilitation
Received: 2022/08/27 | Accepted: 2022/12/15 | Published: 2023/01/21
Received: 2022/08/27 | Accepted: 2022/12/15 | Published: 2023/01/21
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