Write your message
Volume 17, Issue 1 (Iranian Journal of Breast Diseases 2024)                   ijbd 2024, 17(1): 102-115 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Keshtpour Amlashi Z, Bazrafshan M, Shariat Panahi S, Javadi M, aghababaei Z, Tapak L, et al . Assessment of quality of life and its associated factors in nonmetastatic breast cancer patients. ijbd 2024; 17 (1) :102-115
URL: http://ijbd.ir/article-1-1083-en.html
1- , safora2000n@yahoo.com
Abstract:   (1033 Views)
Introduction: Investigating the effective factors on the quality of life in breast cancer patients is of utmost importance in reducing the complications of the disease. The present study aimed to investigate health-related quality of life and its related factors in nonmetastatic breast cancer patients.
Methods: In this cross-section-descriptive-analytical study, 267 patients with nonmetastatic breast cancer were included by simple random sampling method. Pre-diagnostic, diagnostic, and post-treatment information were recorded, and the EORTC Core Quality of Life questionnaire (EORTC QLQ-C30) was administered to study participants.
Results: The results of the X2 statistical analysis also demonstrated that the correlation coefficient between quality of life and age is 0.281, which is statistically significant (P<0.001). Furthermore, the results indicated that the difference in mean quality of life scores among different levels of education, different occupational groups, and marital status was not statistically significant (P=0.605, P=0.096, and P=0.442, respectively). Nonetheless, the difference in mean quality of life scores among individuals in the study across five stage T groups and a history of illness in relatives was statistically significant (P=0.007 and P=0.006, respectively).
Conclusion: The highest quality of life score was related to emotional function; nonetheless,  cognitive function and role play obtained lower scores. Also, age and severity of fatigue affect patients' quality of life. The results of this study emphasize the importance of considering these factors in the management of breast cancer patients in order to improve their quality of life.
Full-Text [PDF 655 kb]   (345 Downloads)    
Type of Study: Research | Subject: Epidemiology
Received: 2023/11/30 | Accepted: 2024/04/5 | Published: 2024/04/25

References
1. Get persistent links for your reference list or bibliography. Copy and paste the list, we’ll match with our metadata and return the links. Members may also deposit reference lists here too. 1. Biparva AJ, Raoofi S, Rafiei S, Kan FP, Kazerooni M, Bagheribayati F, et al. Global quality of life in breast cancer: systematic review and meta-analysis. BMJ Supportive & Palliative Care. 2023;13(e3):e528-e36. [DOI:10.1136/bmjspcare-2022-003642] [PMID] []
2. Corrigan KL, Reeve BB, Salsman JM, Siembida EJ, Andring LM, Geng Y, et al. Health-related quality of life in adolescents and young adults with cancer who received radiation therapy: a scoping review. Supportive Care in Cancer. 2023;31(4):230. [DOI:10.1007/s00520-023-07682-x] [PMID]
3. Inotai A, Ágh T, Maris R, Erdősi D, Kovács S, Kaló Z, et al. Systematic review of real-world studies evaluating the impact of medication non-adherence to endocrine therapies on hard clinical endpoints in patients with nonmetastatic breast cancer. 2021;100:102264. [DOI:10.1016/j.ctrv.2021.102264] [PMID]
4. Alizadeh M, Ghojazadeh M, Piri R, Mirza-Aghazadeh-Attari M, Mohammadi S, Naghavi-Behzad MJIJoPH. Age at Diagnosis of Breast Cancer in Iran: A Systematic Review and Meta-Analysis. 2021;50(8):1564. [DOI:10.18502/ijph.v50i8.6802]
5. Waks AG, Winer EPJJ. Breast cancer treatment: a review. 2019;321(3):288-300. [DOI:10.1001/jama.2018.19323] [PMID]
6. Doege D, Thong MS, Weißer L, Koch-Gallenkamp L, Jansen L, Bertram H, et al. Health-Related Quality of Life in Very Long-Term Cancer Survivors 14-24 Years Post-Diagnosis Compared to Population Controls: A Population-Based Study. 2021;13(11):2754. [DOI:10.3390/cancers13112754] [PMID] []
7. Bjelic-Radisic V, Cardoso F, Cameron D, Brain E, Kuljanic K, da Costa R, et al. An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45. Annals of Oncology. 2020;31(2):283-8. [DOI:10.1016/j.annonc.2019.10.027] [PMID]
8. Licu M, Paun S, Ionescu CG. Quality of Life in Cancer Patients: The Modern Psycho-Oncologic Approach for Romania-a Review. 2023. [DOI:10.20944/preprints202306.0428.v1]
9. Clarijs ME, Oemrawsingh A, Bröker ME, Verhoef C, Lingsma H, Koppert LB. Quality of life of caregivers of breast cancer patients: a cross-sectional evaluation. Health and quality of life outcomes. 2022;20(1):1-10. https://doi.org/10.1186/s12955-022-02028-3 [DOI:10.1186/s12955-022-01930-0] [PMID] []
10. Lewandowska A, Rudzki G, Lewandowski T, Próchnicki M, Rudzki S, Laskowska B, et al. Quality of life of cancer patients treated with chemotherapy. International journal of environmental research and public health. 2020;17(19):6938. [DOI:10.3390/ijerph17196938] [PMID] []
11. Ban Y, Li M, Yu M, Wu H. The effect of fear of progression on quality of life among breast cancer patients: the mediating role of social support. Health and Quality of Life Outcomes. 2021;19(1):1-9. [DOI:10.1186/s12955-021-01816-7] [PMID] []
12. Di Francesco M, Celia C, Cristiano MC, d'Avanzo N, Ruozi B, Mircioiu C, et al. Doxorubicin hydrochloride-loaded nonionic surfactant vesicles to treat metastatic and nonmetastatic breast cancer. 2021;6(4):2973-89. [DOI:10.1021/acsomega.0c05350] [PMID] []
13. Husson O, de Rooij BH, Kieffer J, Oerlemans S, Mols F, Aaronson NK, et al. The EORTC QLQ‐C30 summary score as prognostic factor for survival of patients with cancer in the "real‐world": Results from the population‐based PROFILES registry. The oncologist. 2020;25(4):e722-e32. [DOI:10.1634/theoncologist.2019-0348] [PMID] []
14. Giesinger JM, Loth FL, Aaronson NK, Arraras JI, Caocci G, Efficace F, et al. Thresholds for clinical importance were established to improve interpretation of the EORTC QLQ-C30 in clinical practice and research. Journal of clinical epidemiology. 2020;118:1-8. [DOI:10.1016/j.jclinepi.2019.10.003] [PMID]
15. Montazeri A, Harirchi I, Vahdani M, Khaleghi F, Jarvandi S, Ebrahimi M, et al. The EORTC breast cancer-specific quality of life questionnaire (EORTC QLQ-BR23): translation and validation study of the Iranian version. 2000;9(2):177-84. [DOI:10.1023/A:1008918310251] [PMID]
16. Ford ME, Havstad SL, Kart CS. Assessing the reliability of the EORTC QLQ-C30 in a sample of older African American and Caucasian adults. Quality of Life Research. 2001;10:533-4117. [DOI:10.1023/A:1013003014340] [PMID]
17. Safaee A, Moghimi-Dehkordi B, Zeighami B, Tabatabaee H, Pourhoseingholi M. Predictors of quality of life in breast cancer patients under chemotherapy. Indian journal of cancer. 2008;45(3):107-11. [DOI:10.4103/0019-509X.44066] [PMID]
18. Cancer IAfRo. World cancer report: World Health Organization: IARC Press; 2003.
19. Poorkiani M, Abbaszadeh A, Hazrati M, Jafari P, Sadeghi M, Mohammadianpanah M. The effect of rehabilitation on quality of life in female breast cancer survivors in Iran. Indian Journal of Medical and Paediatric Oncology. 2010;31(04):105-9. [DOI:10.4103/0971-5851.76190] [PMID] []
20. Salati M, Brunelli A, Xiume F, Refai M, Sabbatini A. Quality of life in the elderly after major lung resection for lung cancer. Interactive cardiovascular and thoracic surgery. 2009;8(1):79-83. [DOI:10.1510/icvts.2008.184986] [PMID]
21. Afsane B, Mahmoud H. [5 year assessment of breast cancer at rajaii hospital, babolsar [1991-1996]]. 2006.
22. Najjar H, Easson AJIjos. Age at diagnosis of breast cancer in Arab nations. 2010;8(6):448-52. [DOI:10.1016/j.ijsu.2010.05.012] [PMID]
23. Özmen V, Özmen T, Doğru VJEjobh. Breast cancer in Turkey; an analysis of 20.000 patients with breast cancer. 2019;15(3):141.
24. Schlichting JA, Soliman AS, Schairer C, Harford JB, Hablas A, Ramadan M, et al. Breast cancer by age at diagnosis in the Gharbiah, Egypt, population-based registry compared to the United States surveillance, epidemiology, and end results program, 2004-2008. 2015;2015. [DOI:10.1155/2015/381574] [PMID] []
25. Karim SAM, Ghalib HHA, Mohammed SA, Fattah FHRJIJoS. The incidence, age at diagnosis of breast cancer in the Iraqi Kurdish population and comparison to some other countries of Middle-East and West. 2015;13:71-5. [DOI:10.1016/j.ijsu.2014.11.029] [PMID]
26. Lee J, Oh MJBwsh. Effects of interval between age at first pregnancy and age at diagnosis on breast cancer survival according to menopausal status: a register-based study in Korea. 2014;14(1):1-8. [DOI:10.1186/1472-6874-14-113] [PMID] []
27. Mehdi I, Monem EA, Al Bahrani BJ, Al Kharusi S, Nada AM, Al Lawati J, et al. Age at diagnosis of female breast cancer in Oman: Issues and implications. 2014;3(02):101-6. [DOI:10.4103/2278-330X.130442] [PMID] []
28. Missaoui N, Landolsi H, Jaidaine L, Abdelkader AB, Yaacoubi MT, Hmissa SJTbj. Breast cancer in Central Tunisia: An Earlier Age at Diagnosis and Incidence Increase over a 15‐Year Period. 2012;18(3):289-91. [DOI:10.1111/j.1524-4741.2012.01242.x] [PMID]
29. Afsharfard A, Mozaffar M, Orang E, Tahmasbpour EJAPJoCP. Trends in epidemiology, clinical and histopathological characteristics of breast cancer in Iran: results of a 17 year study. 2013;14(11):6905-11. [DOI:10.7314/APJCP.2013.14.11.6905] [PMID]
30. Haghighat S, Akbari M, Ghaffari S, Yavari PJAPJoCP. Standardized breast cancer mortality rate compared to the general female population of Iran. 2012;13(11):5525-8. [DOI:10.7314/APJCP.2012.13.11.5525] [PMID]
31. Baghestani AR, Shahmirzalou P, Zayeri F, Akbari ME, Hadizadeh MJAPJoCP. Prognostic factors for survival in patients with breast cancer referred to omitted cancer research center in Iran. 2015;16(12):5081-4. [DOI:10.7314/APJCP.2015.16.12.5081] [PMID]
32. Monfared A, Pakseresht S, Ghanbari A, ATRKAR RZ. Health-Related Quality of Life and its related factors among women with breast cancer. 2014.
33. Rezaei R, Saatsaz S, Haji Hosseini F, Sharifnia S, Nazari R. Quality of life in gynecologic cancer patients before and after chemotherapy. Journal of Babol University of Medical Sciences. 2011;13(4):78-84.
34. Tahmasebi M, Yarandi F, Eftekhar Z, Montazeri A, Namazi H. Quality of life in gynecologic cancer patients. Asian Pac J Cancer Prev. 2007;8(4):591-2.
35. Miller BE, Pittman B, Case D, McQuellon RP. Quality of life after treatment for gynecologic malignancies: a pilot study in an outpatient clinic. Gynecologic oncology. 2002;87(2):178-84. [DOI:10.1006/gyno.2002.6812] [PMID]
36. Smith AW, Alfano CM, Reeve BB, Irwin ML, Bernstein L, Baumgartner K, et al. Race/ethnicity, physical activity, and quality of life in breast cancer survivors. Cancer Epidemiology Biomarkers & Prevention. 2009;18(2):656-63. [DOI:10.1158/1055-9965.EPI-08-0352] [PMID] []
37. DeSantis C, Siegel R, Jemal AJACS. Cancer treatment and survivorship: facts and figures 2014-2015. 2014;2015:3-6.
38. Safaee A, Moghimi-Dehkordi B, Zeighami B, Tabatabaee H, Pourhoseingholi MJIJoC. Predictors of quality of life in breast cancer patients under chemotherapy. 2008;45(3):107. [DOI:10.4103/0019-509X.44066] [PMID]
39. Chagani P, Parpio Y, Gul R, Jabbar AAJA-Pjoon. Quality of life and its determinants in adult cancer patients undergoing chemotherapy treatment in Pakistan. 2017;4(2):140-6. [DOI:10.4103/2347-5625.204499] [PMID] []
40. Heydarnejad MS, Hassanpour DA, Solati DKJAhs. Factors affecting quality of life in cancer patients undergoing chemotherapy. 2011;11(2):1-3
41. Karami O, Falahat-Pisheh F, Jahani Hashemi H, Beiraghdar NJJoID. Quality of life in cancer patients in Qazvin (2007). 2010;14(3):80-6.
42. Rezaei R, Saatsaz S, Haji Hosseini F, Sharifnia S, Nazari RJJoBUoMS. Quality of life in gynecologic cancer patients before and after chemotherapy. 2011;13(4):78-84.
43. Mkanta WN, Chumbler NR, Richardson LC, Kobb RFJCn. Age-related differences in quality of life in cancer patients: a pilot study of a cancer care coordination/home-telehealth program. 2007;30(6):434-40. [DOI:10.1097/01.NCC.0000300167.80466.91] [PMID]
44. Shahsavari H, Matory P, Z. Z. correlation between quality of life in patients with advanced prostate cancer in seiedalshada hospital in isfahan in 2013. Community Health J 2017;9(1):58-67.
45. Denkinger MD, Hasch M, Gerstmayer A, Kreienberg R, Nikolaus T, Hancke K. Predicting fatigue in older breast cancer patients receiving radiotherapy. Zeitschrift für Gerontologie und Geriatrie. 2015;2(48):128-34. [DOI:10.1007/s00391-014-0840-5] [PMID]
46. Özkan M, Semiha A. Evaluation of the effect of fatigue on functional quality of life in cancer patients. Florence Nightingale Journal of Nursing. 2017;25(3):177-92. [DOI:10.17672/fnjn.343256]
47. Hasanvand S, Ashktorab T, Jafari Z, Salmani N, Safariyan ZJAiN, Midwifery. Cancer-related fatigue and its association with health-related quality of. 2015;24(85):21-30.
48. Charalambous A, Kouta CJBri. Cancer related fatigue and quality of life in patients with advanced prostate cancer undergoing chemotherapy. 2016;2016. [DOI:10.1155/2016/3989286] [PMID] []
49. Yeo TP, Cannaday SJNr, reviews. Cancer-related fatigue: impact on patient quality of life and management approaches. 2015;5:65-76. [DOI:10.2147/NRR.S41957]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Iranian Journal of Breast Diseases

Designed & Developed by: Yektaweb